Jingyoujia® - The "Guardian" of Aquaculture

Vibrio bacteria are like invisible killers, silently threatening the health of aquatic animals. Vibriosis is the most common bacterial disease in aquaculture. Vibrio bacteria enter aquatic animals through oral transmission or through body surface wounds and gills, causing diseases that can lead to mortality rates as high as over 90% in severe cases.

Cocrystal Technology's independently developed patented product (ZL202110209829.2) - Jingyoujia®, applies pharmaceutical cocrystal technology to combine thymol/carvacrol with proline at a 1:1 molar ratio, forming a macroscopic crystalline powder. This improves the stability of bioactive molecules, increases the water solubility (completely and rapidly soluble) and absorption efficiency of active ingredients, while reducing product volatility and eliminating odor interference. In practical applications, Jingyoujia® has demonstrated excellent efficacy in inhibiting Vibrio bacteria.

Practical Validation of Jingyoujia®

1. Validation by an Aquaculture Cooperative in a Town in Nantong, Jiangsu (March 16, 2024)

Test Method: The thiosulfate-citrate-bile salts-sucrose (TCBS) Vibrio medium method was used to evaluate the inhibitory effect of Jingyoujia® on green Vibrio bacteria. The tested concentrations of Jingyoujia® were 0.1%, 0.2%, and 0.3%.

Test Results: As shown in Figures 1 to 4, compared with the control group, Jingyoujia® at concentrations of 0.1%, 0.2%, and 0.3% all showed significant inhibitory effects on green Vibrio bacteria.

(Figures 1-4 show comparative images of culture media from the control group and Jingyoujia® groups at different concentrations, clearly demonstrating inhibition zones.)

2. Validation by OTON (Nantong) Shrimp Pathogen Detection Research Center (May 19, 2024)

Test Method: The TCBS Vibrio medium method was used to evaluate the inhibitory effect of Jingyoujia® (at a concentration of 0.2%) on Vibrio parahaemolyticus in shrimp.

Test Results: As shown in Table 1, Jingyoujia® had a significant inhibitory effect on Vibrio parahaemolyticus in shrimp. On the third day of using Jingyoujia®, Vibrio parahaemolyticus was not detected.

Table 1 Test results of Jingyoujia®'s effect on Vibrio parahaemolyticus in shrimp

Note: Customer number 28 is the test result of the control group; customer number 32 is the test result of Jingyoujia® used for 1 day; customer number 37 is the test result of Jingyoujia® used for 2 days; customer number 57 is the test result of Jingyoujia® used for 3 days

3. Validation by a Animal Health Company in Shandong (April 3, 2024)

Test Method: The TCBS Vibrio medium method was used to evaluate the inhibitory effect of Jingyoujia® on yellow Vibrio bacteria. The tested concentrations of Jingyoujia® were 0.05%, 0.1%, 0.5%, and 1%.

Test Results: As shown in Figure 5, compared with the negative control group, both the positive control group (a certain antibiotic) and the Jingyoujia® groups showed significant inhibitory effects on yellow Vibrio bacteria. There was no significant difference in the inhibitory effects between the positive control group and the Jingyoujia® groups.

(Figure 5 shows: the negative control group was covered with yellow Vibrio colonies, while both the positive control group and the Jingyoujia® groups displayed clear inhibition zones with comparable efficacy.)

Product Advantages of Jingyoujia®

• High-efficiency bacteriostasis: Jingyoujia® can significantly inhibit the growth of Vibrio bacteria at various concentrations, effectively preventing the occurrence of vibriosis.
• High safety: The composition of Jingyoujia® is clearly defined and has been strictly verified by third-party laboratories, showing no harm to aquatic organisms.
• Easy to use: Jingyoujia® is completely and rapidly soluble, suitable for use in various scenarios.
• Cost-effective: Compared with other bacteriostatic products, Jingyoujia® offers higher cost-performance.

Jingyoujia®, with its excellent bacteriostatic properties, safety, and economy, protects your aquaculture business, making farming healthier and more efficient. Cocrystal Technology, work with you to create a better future.

Address: Zhejiang | Jiaxing

Official Website: www.cocrystaltech.com

Email: [email protected]

Phone: 0573-84583582

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