Cocrysta® Curcumin

A highly bioavailable anti-inflammatory that supports joint health, enhances immune function, and promotes overall well-being.

Patent protected
60 times higher absorption based on published clinical trials
Synergistic liver protection with L-carnitine

Benefits
Why Cocrysta®
What Cocrysta® does
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Benefits

Curcumin is a plant polyphenol derived from the roots and stems of ginger and araceae plants. Known for its strong anti-inflammatory and antioxidant properties, curcumin is widely used in supplements, functional foods, and traditional medicines.

Liver Protection
Weight Management
Joint Health
Emotional Well-being

Why Cocrysta®

Traditional curcumin suffers from low water solubility (< 1 μg/mL) and a frustrating bioavailability of less than 1%. This means that to experience any therapeutic effects, you’d need to take high doses of 2-3 grams a day.

Unlock the full potential of the ingredient with Cocrysta® Curcumin. Powered by cutting-edge cocrystallization technology, our innovative formula not only significantly improves solubility but also boasts a remarkable 60 times higher bioavailability.

Higher Solubility

Compared with general curcumin, the maximum solubility of Cocrysta® Curcumin is increased by 30 times in simulated gastric fluid (SGF) and 60 times in simulated intestinal fluid (SIF).
Enhanced Bioavailability-Animal Study

Animals: 12 male SD rats were divided into two groups, with 6 rats in each group.
Dosage: 200 mg/kg (curcumin equivalent)
Results: Compared with general curcumin, Cocrysta® Curcumin displays higher absorption, with 10.7 times higher C_max and 6.3 times higher AUC_0-24.
Enhanced Bioavailability-Human Study

Subject: 12 healthy subjects（Male，Age: 18-45，BMI: 18.5-30）
Design: Randomized, Double-blinded, Cross-over.
Dosage: 1000 mg
Test Product: Cocrysta® Curcumin hard capsule（Cocrysta® Curcumin）
Reference Product: D* ® Curcumin hard capsule（ Curcumin + Piperine）
Results: Compared with those of the combination of curcumin and piperine, the C_max and AUC_0-24h of Cocrysta® Curcumin were increased by 2.8 times and 2.7 times, respectively. This means Cocrysta® Curcumin enhances absorption by remarkable 60 times compared to standard curcumin.
Superior Hepatoprotective Effects

Animals: 40 model rats with non-alcoholic fatty liver disease (NAFLD)
Groups: CD60: blank solution, CUR: conventional curcumin, CUR-CAR: Cocrysta® Curcumin.
Results: Cocrysta® Curcumin group demonstrated significantly better therapeutic efficacy than both groups of control and conventional curcumin, with ALT reduced by 46.94% and AST by 22.14%.