Cocrysta Reduced CoQ10: 8x Better Absorption, More Forms

Cocrysta® Reduced Coenzyme Q10: 8 Times Better Absorption, Breaking Through the Limitations of Single-Dosage-Form Products on the Market

Coenzyme Q10 is a popular raw material in the nutrition and health field. However, the stability issue of reduced coenzyme Q10 has long plagued brands and manufacturers. The emergence of cocrystal technology provides a brand new answer to this problem.

The Two Forms of Coenzyme Q10 and Industry Pain Points

Coenzyme Q10 exists in two forms: oxidized (ubiquinone) and reduced (ubiquinol). In the human body, it is the reduced form that exerts true physiological activity, accounting for over 95% of the active form in the blood. However, the molecular characteristics of reduced coenzyme Q10 are inherently limited. It is highly susceptible to oxidation and deactivation upon exposure to light and oxygen. This not only incurs high protective costs during storage and transportation but also imposes numerous restrictions on dosage form development.

Addressing these long-standing raw material pain points, Cocrystal Technology provides a completely different solution from the molecular level.

Cocrystal Technology – Nutritional Reconstruction at the Molecular Level

What is cocrystal technology?

Cocrystal technology originates from the field of pharmaceutical research and development and is a mature crystal engineering technique. In simple terms, cocrystallization involves combining active ingredient molecules with GRAS (Generally Recognized as Safe) ligand molecules through non-covalent bonds, like "hand-in-hand", to construct a completely new, rearranged crystal lattice system. This new lattice does not change the chemical structure of the active ingredient but rearranges the molecular arrangement at the physical level.

What can cocrystal technology change?

• Locking in Stability: The new crystal lattice structure "locks" the active molecules firmly, blocking chain reactions with oxygen and free radicals, ensuring the active ingredient remains stable throughout its entire life cycle.
• Enhancing Absorption Rate: Hydrophilic ligand molecules act like "molecular chaperones", guiding the formation of supersaturated solutions, extending the absorption time window, and achieving several-fold or even tens-fold increases in absorption.
• Enabling Clean Labels: The preparation process does not require the addition of excess auxiliaries, reducing the use of stabilizers and antioxidants. This results in a streamlined and pure formulation that aligns with the clean label market trend.
• Expanding Dosage Form Compatibility: The cocrystallized raw materials possess better processing adaptability, breaking through the limitations of traditional dosage forms. They can be adapted to various forms, including soft and hard capsules, tablets, functional gummies, and powders.

Cocrysta® Reduced Coenzyme Q10: Let the Data Speak

• Up to 8 Times Higher Absorption Rate: Randomized, double-blind, crossover controlled human clinical studies have confirmed that compared to traditional oxidized Coenzyme Q10, the total in vivo absorption (AUC) of the Cocrysta® product is increased by up to 8 times. 100% of the subjects participating in the trial showed positive absorption gains.

• Patents Granted in China, the United States, and Japan: Cocrysta® Reduced Coenzyme Q10 has obtained substance patents in China, the United States, and Japan, establishing the exclusivity and originality of the technology at the molecular level.
• 98% High Retention Stability: When left open for 4 weeks, the activity of commercially available ordinary reduced coenzyme Q10 degrades by over 70%. In contrast, the activity retention rate of Cocrysta® Cocrystal Reduced Coenzyme Q10 can reach over 98%. Even after 36 months of long-term storage, the active content remains stably above 98%, and normal temperature storage and transportation do not require nitrogen gas sealing.

• Full Coverage of Mainstream Dosage Forms: The most common dosage form for traditional reduced coenzyme Q10 on the market is the soft capsule, making dosage form selection extremely limited. Cocrysta® Reduced Coenzyme Q10 is compatible with various forms, including soft and hard capsules, tablets, functional gummies, and powders. It also works well with various raw material combination formulas, helping brands create differentiated products.

Global Brands Are Starting to Choose Cocrystal Technology

Cocrystal Technology provides a brand new, high-performance technological route for the global nutrition and health market, winning a voice in the global market with product strength.

The Practical Value Brought by Cocrystal Products:

• Longer shelf life and lower storage costs – normal temperature storage and transportation are sufficient, eliminating the need for nitrogen gas sealing, reducing production and logistics costs.
• Clean label – the raw material itself is pure, requiring no large amounts of antioxidants or stabilizing excipients, resulting in a cleaner formulation.
• More stable production delivery – high activity retention rate, strong batch-to-batch consistency, reducing production concerns.
• Better consumer repurchase – high absorption rate and good user experience naturally lead to positive word-of-mouth.

To date, Cocrystal Technology's Cocrysta® series of cocrystal raw materials includes several core products such as reduced coenzyme Q10, curcumin, lutein, silybin, and urolithin A. Leveraging exclusive substance patents and significant performance advantages, the company has successfully entered the supply chain of numerous leading domestic and international health brands. Its clients cover top domestic dietary supplement brands, internationally renowned high-end nutrition brands, and leading companies in vertical fields. This fully validates the reliability and competitiveness of cocrystal technology in large-scale commercial applications.

Technological breakthroughs are never meant to replace others, but to offer the market a better choice. This choice ultimately reaches every consumer – providing purer raw materials, delivering a more efficient health experience, reducing the burden on the body, and improving the quality of life.

Address: Zhejiang | Jiaxing

Official Website: cocrystaltech.com

Email: [email protected]

Phone: 0573-84583582